The first pediatrician with training and practice in Molecular Allergology. She graduated in Medicine in 1977 at the Rome University "Sapienza" and specialized in Pediatrics in 1980 and in Childcare in 1985. For over 25 years, she was interested in pediatric allergy and for more than 10 years she has begun her personal journey in Molecular Allergology. Extremely interested in the matter, since the beginning of 2008 she has transferred her business from one of the largest departments of pediatrics in Rome to the Molecular Allergology Center, by integrating her healthcare activity with that of research in the pediatric age, effectively complementing the activities already taking place in the center and dedicated to teenagers, adults and seniors. She has performed some fundamental studies on markers of severity of food allergy in children, mainly in cow's milk, egg, and plant food allergy. In collaboration with the other CAAM members and researchers from other research centers, she has identified and characterized new allergenic molecules and, thanks to microarray-based diagnostics, she has set new molecular profiles of awareness leading to innovative schemes for therapeutic intervention in the allergic child. Dr.ssa Alessandri is co-author of 33 scientific papers, 23 of which in collaboration with other CAAM members. She is co-founder of CAAM, sharing the spirit and philosophy, contributing to its organization and its development. Together with the other CAAM specialists she contributes to the design and release of the second generation molecule-based test for allergy diagnosis, the FABER IgE test.
Specialist and laboratory researcher. She graduated in Medicine in 1994 at the Rome University "Sapienza", got her specialty degree in Allergy and Clinical Immunology in 1999, and graduated as PhD in Science of Immunological therapies in 2006. After her time at university dedicated to the healthcare and research in HIV disease, in 2006 she, first among the members of the Founders CAAM, joined the Center of Molecular Allergology, where she began and developed her work related to the clinical and immunological characterization of new allergenic molecules. Many of these new molecules have increased the number of allergens on the ISAC microarray, and have created a new "flexible" microarray called ABA (Allergen Beads Array) for which Dr.ssa Bernardi has given the greatest contribution in research and development. Her description of the different clinical and immunological reactivity to homolog or not homolog allergens has contributed to the development of new therapeutic interventions in patients with food allergy. She is co-author of 32 scientific papers including 26 in collaboration with other CAAM members. She is co-founder of the CAAM, actively and originally contributing with her clinical activities and research. Together with the other CAAM specialists she contributes to the design and release of the second generation molecule-based test for allergy diagnosis, the FABER IgE test.
Specialist with a unique clinic imprinting. She graduated in Medicine at the Rome University "Sapienza" in 1991, and got the specialty in Allergology and Clinical Immunology in 1995. After the university activity in clinical trials in HIV disease, she has continued her clinical experience in an internal medicine hospital ward. Since 2006, she has entered in the Center of Molecular Allergology, where she became responsible for clinical trials in both the comparative characterization of different reactivity of allergenic extracts and in the identification, characterization and preparation of new molecular compounds in the laboratory of the Centre and in research centers with which she collaborated. She has been reference clinician for international trials where the Centre of Molecular Allergology was the only Italian partner. Among others, the project FAST-EU for the study of specific immunotherapy in allergy to food allergens, plant-derived food LTP and fish parvalbumin. She has been responsible for the international clinical trial for the use of Omalizumab in the treatment of chronic urticaria. Dr.ssa Ferrara is co-author of 40 scientific papers including 24 in collaboration with other CAAM members. She is co-founder of the CAAM, actively contributing to clinical research. Together with the other CAAM specialists she contributes to the design and release of the second generation molecule-based test for allergy diagnosis, the FABER IgE test.
Molecular Allergology forerunner. Specialist graduated in Medicine at the Rome University "Sapienza" in 1980, got the specialty in Allergology in 1983. He added to his clinical training the activity as researcher in the laboratory, with a long lasting collaboration with the Laboratory of Immunology at the Italian National Institute of Health (1984-2000) where he learned all the biochemical an immunochemical techniques, and the development of murine models. Among other activities, he acquired the basics of programming on personal computers, creating the first database of low molecular weight compounds causing allergies (i.e. drug, hapten, occupational allergens). At the end of the eighties, in the pre-Internet era he produced a report for the Council of Europe, funding the project, including 1,500 compounds and their chemical, immunological and clinical features. Since the early nineties he resumed his clinical allergology practice as allergist working in local settings of the Italian National Healthcare System. In the second half of the nineties he brought together all his expertise, clinical, laboratory and information technology, in the great project of Molecular Allergology leading to the identification of many allergenic molecules, to the development of microarrays as the main tool for investigations in allergy diagnostics, the creation of the Allergome web platform, the development of its external modules, the electronic record InterAll, the AllergomeConsumer project, and the initial development of Apps for mobile devices, and for their integrated use in the clinic and in research. Dr. Mari is the author and co-author of 154 scientific papers, 43 of them in collaboration with other CAAM members. He is a member of the Subcommittee for the Standardization and Quality Assessment of Immunological Diagnostics of the International Union of Immunological Societies. He has been the creator of the first Center for Molecular Allergology and is co-founder of the CAAM, which helps with organizational activities, coordination and developments. Currently, he has unanimously been appointed by the other Associates Founder, Director and Representative of the CAAM. Together with the other CAAM specialists he contributes to the design and release of the second generation molecule-based test for allergy diagnosis, the FABER IgE test and of the original dynamic visualization system of the test results, the CDRS.
Medical specialist with immunological training in autoimmune diseases and allergy. She graduated in Medicine at the Rome University "Campus Bio-Medico" in 2003, and obtained the specialty in Allergology and Clinical Immunology in 2007, discussing for the first time in Italy a thesis in Molecular Allergology. She is the first specialist to qualify as molecular allergist from the start of her professional career. The initial training in autoimmune disease, in which for decades molecular antigens have been used in the diagnosis of various diseases, led her without hesitation to the new world of molecular allergology. She has entered in the Center of Molecular Allergology since 2006, becoming a member in 2007. She has contributed to all clinical and research activities, beginning at the same time an independent research path dealing with the use of microarray molecular either in its routine applications or, with a new experimental version, dealing with very complex issues that unite allergy to other aspects of immunology as autoimmunity, immunodeficiency, cancer pathology, and occupational allergy. Dr.ssa Zennaro is co-author of 28 scientific papers including 21 in collaboration with other CAAM members. She is co-founder of the CAAM, in whose organization contributes actively, expanding the clinical and research activities. Together with the other CAAM specialists she contributes to the design and release of the second generation molecule-based test for allergy diagnosis, the FABER IgE test.
Chiara Rafaiani: She collaborates with the Center for Molecular Allergology since 2007. She is the laboratory technician of the CAAM who performed a global record of 30 000 molecular tests during the past eight years, currently operating in the CAAM laboratory at Sermolab S.r.l., being also responsible for laboratory research. She actively contributed to the fine development of the new test FABER for the diagnosis of IgE-mediated allergic diseases.
The CAAM professionals and researchers directly contribute with their scientific production to the growth of knowledge in the field of allergy and immunology. They carefully acquire results of studies carried out in all countries worldwide and published in the scientific literature.
While contributing to the management and updating of the Allergome platform, the CAAM constantly acquires this knowledge. The dynamic bibliographic database, managed by means of a dedicated archive (Reference Manager for Allergome) created by ADL for Allergome and exclusively available for Associated CAAM members, consists of about 138,000 scientific papers published in the last hundred years. Weekly updates, consisting of approximately 150 to 200 items, undergo continuous reading and critical reviewing, as well as food for training, discussion and debate among the CAAM specialists.
Società Italiana di Allergologia ed Immunologia Clinica (SIAIC)
European Academy of Allergology and Clinical Immunology (EAACI)
Associazione Italiana di Aerobiologia (AIA)
International Association of Aerobiology (IAA)
Associazione Allergologi Immunologi Territorio e Ospedalieri (AAITO)
International Immunomics Society
Honored Member of the Cuban Society of Immunology